Large transient assemblies of Apaf1 constitute the apoptosome in cells
Alicia C. Borgeaud, Iva Ganeva, Calvin Klein, Amandine Stooss, Daniela Ross‐Kaschitza, Liyang Wu, Joel S. Riley, Stephen W. G. Tait, Thomas Lemmin, Thomas Kaufmann, Wanda Kukulski
The paper shows that Apaf1 forms transient foci during apoptosis, which correspond to the apoptosome and regulate apoptosis progression.
Nature Communications · Oct 24, 2025Peer-reviewedCell Biology