Laser-driven VHEE pulsed fast fractionation (PFF): second-scale inter-pulse timing can modulate normal tissue toxicity in vivo
Camilla Giaccaglia, Émilie Bayart, Chaitanya Varma, J.-P. Goddet, J. Gautier, Amar Tafzi, Emilie Menant, Isabelle Lamarre, Sophie Heinrich, Charles Fouillade, A. Flacco
This paper shows that varying second-scale inter-pulse intervals in pulsed fast fractionation (PFF) with VHEE radiation can differentially modulate normal tissue toxicity and cell viability in vitro and in vivo.
bioRxiv · Sep 12, 2026 · PreprintCell Biology