A prophage-encoded sRNA limits lytic phage infection of adherent-invasive E. coli
Robert S. Brzozowski, Amelia K. Schmidt, Nicole L. Pershing, Annika Dankwardt, Dominick R. Faith, Alex C. Joyce, Andrew Maciver, William S. Henriques, Shelby E. Andersen, Blake Wiedenheft, Sherwood Casjens, Breck A. Duerkop, June L. Round, Patrick R. Secor
The paper identifies a prophage-encoded sRNA, svsR, that reduces lytic phage infection in AIEC by repressing maltodextrin transport genes, thereby limiting phage receptor expression.
bioRxiv · May 6, 2025 · PreprintMicrobiology