Nociceptor Neurons Control Pollution-Mediated Neutrophilic Asthma
Jo-Chiao Wang, Amelia Kulle, Théo Crosson, Amin Reza Nikpoor, Surbhi Gupta, Anais Roger, Moutih Rafei, Ajitha Thanabalasuriar, Sébastien Talbot
This study shows that nociceptor neurons contribute to pollution-induced neutrophilic asthma by enhancing TRPA1 sensitivity and artemin release, which drives neutrophil recruitment.
eLife · Mar 27, 2026Peer-reviewedImmunology