Sébastien Talbot

This study shows that nociceptor neurons contribute to pollution-induced neutrophilic asthma by enhancing TRPA1 sensitivity and artemin release, which drives neutrophil recruitment.

This study shows that nociceptor neurons promote immunosuppression in tumors by increasing MDSC infiltration and CD8+ T cell exhaustion through IL-6 and sEVs.

The paper investigates how IL-13 reprograms airway nociceptor neurons during asthma, promoting sensory-sympathetic neuron crosstalk through NPY1R signaling.

The paper identifies basophils as a source of oncostatin M that activates vagal pruriceptor neurons during allergic responses.

This paper develops a novel cationic compound, BW-031, that effectively inhibits cough by targeting large pore-expressing airway sensory neurons through aerosolized delivery.