Estimating Heritability of Glycaemic Response to Metformin using Nationwide Electronic Health Records and Population-Sized Pedigree
Iris N. Kalka, Amir Gavrieli, Smadar Shilo, Hagai Rossman, Nitzan Shalom Artzi, Nancy‐Sarah Yacovzada, Eran Segal
The paper estimates the heritability of metformin's glycaemic response using EHR data and population pedigrees, finding a heritability of 10.5-12.2%.
Communications Medicine · Dec 1, 2021Peer-reviewedGenetic & Genomic Medicine