An optopharmacological tool for on-demand perturbation of branched actin polymerization
Srishti Mandal, Alka Chahal, Steve Chung, Arka Som, Kamal Kishore, Parinaz A. Shekari, Amit Baidya, Kavita Babu, Michael Mak, Jonathon A. Ditlev, Sarit S. Agasti, Sudha Kumari
The paper introduces a photocrosslinkable inhibitor, AZ, to selectively and spatiotemporally control Arp2/3 complex-dependent actin nucleation in live cells.
bioRxiv · May 29, 2026 · PreprintCell Biology