Author

Amity L. Manning

Worcester Polytechnic Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Elizabeth A. Crowley· 1 shared

Activity by Year

2025-2025 · peak 1/yr

1 paper

Recent·Most cited

RB dependent transcriptional regulation at mitotic centromeres preserves genome stability

Elizabeth A. Crowley, Amity L. Manning

This study shows that RB regulates centromere transcription during mitosis, and its loss leads to increased RNA Pol II activity, DNA breaks, and mitotic defects.

Life Science Alliance · Dec 12, 2025Peer-reviewedCell Biology