Restoration of high-sensitivity patterned vision in motion with an engineered light-gated G protein-coupled receptor
Amy Holt, Michael H. Berry, Jamie Lo, Prashant Donthamsetti, Meike Visel, Johannes Broichhagen, John G. Flannery, Ehud Y. Isacoff
This paper demonstrates a chemical-optogenetic approach that restores high-sensitivity motion vision in an IRD mouse model using a multi-branched photoswitch.
bioRxiv · Apr 7, 2022 · PreprintNeuroscience