Matrix stiffness and stress relaxation regulate osteogenesis through histone demethylases KDM4B and KDM6B
Ian M. Tayler, Amy Zhu, Abhishek Sharma, Neha Saxena, Siddharth S. Dey, Ryan S. Stowers
This study shows that matrix stiffness and stress relaxation influence osteogenesis by regulating histone demethylases KDM4B and KDM6B through mechanotransduction signaling.
Molecular Biology of the Cell · Mar 11, 2026Peer-reviewedCell Biology