Hepatocyte ERα orchestrates sex-specific liver adaptation to fasting and feeding states
Blandine Tramunt, Marie-Lou Calmy, Arnaud Polizzi, Marine Huillet, Naia Grandgeorge, Ana Avalrez-Tena, Sarra Smati, Tiffany Fougeray, Frédéric Boudou, Marion Régnier, Anne Fougerat, Stéphanie Gayral, Frédéric Lasserre, Claire Naylies, Yannick Lippi, , Alexandra Montagner
This study shows hepatocyte ERα regulates sex-specific liver responses to fasting and feeding, affecting gene expression and metabolic pathways differently in males and females.
bioRxiv · Dec 9, 2025 · PreprintPhysiology