Author

Sarra Smati

Centre Hospitalier Universitaire de NantesORCID 0000-0002-5749-983XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Physiology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Alexandra MontagneriD· 3 shared Anne FougeratiD· 3 shared Arnaud PolizziiD· 3 shared Claire Naylies· 3 shared Marine HuilletiD· 3 shared Nicolas LoiseauiD· 3 shared Yannick LippiiD· 3 shared Bart StaelsiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersPhysiology

Alexandra MontagnerORCID

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3 papers

Recent·Most cited

PhysiologybioRxivPreprintOct 11, 2026

The constitutive androstane receptor protects against metabolic dysfunction-associated steatotic liver disease through sex specific interactions with the gut microbiota

Marine Huillet, Céline M P Martin, Guillaume Magne…·Sandrine Ellero‐Simatos

This study shows that the constitutive androstane receptor (CAR) protects against MASLD in males through interactions with gut microbiota, but not in females.

DOI 10.64898/2026.10.08.757558

mousebulk RNA-seq

𝕏 PostBluesky

Pharmacology & ToxicologybioRxivPreprintOct 7, 2026

PPARα-dependent effects in the liver and jejunum of mice in response to pemafibrate

Frédéric Lasserre, Arnaud Polizzi, Anne Fougerat…·Elena Piccinin

This study examines pemafibrate's tissue-specific transcriptional effects in PPAR-dependent mice, showing strong responses in liver and jejunum but not in other tissues.

DOI 10.64898/2026.09.30.755633

mousebulk RNA-seq

𝕏 PostBluesky

PhysiologybioRxivPreprintDec 9, 2025

Hepatocyte ERα orchestrates sex-specific liver adaptation to fasting and feeding states

Blandine Tramunt, Marie-Lou Calmy, Arnaud Polizzi…·Alexandra Montagner

This study shows hepatocyte ERα regulates sex-specific liver responses to fasting and feeding, affecting gene expression and metabolic pathways differently in males and females.

DOI 10.64898/2025.12.05.692559

mousebulk RNA-seq

𝕏 PostBluesky