Author

Ana R Moshkovsky

Harvard University

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Systems Biology· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Marc W. KirschneriD· 2 shared Wenzhe MaiD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

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2 shared papersSystems Biology

Marc W. KirschnerORCID

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2 papers

Recent·Most cited

Systems BiologyProceedings of the National Academy of SciencesPeer-reviewedFeb 23, 2022

The non-redundant nature of the Axin2 regulatory network in the canonical Wnt signaling pathway

Ana R Moshkovsky, Marc W. Kirschner

The paper demonstrates that Axin1 and Axin2 form a nested feedback system providing regulatory versatility despite their functional redundancy in the Wnt pathway.

33 citations

mousehuman

𝕏 PostBluesky

Systems BiologybioRxivPreprintMay 5, 2021

The self-regulated response of the Wnt pathway to an oncogenic mutation in β-catenin

Ana R Moshkovsky, Wenzhe Ma, Marc W. Kirschner

The paper investigates how an oncogenic mutation in β-catenin affects the Wnt pathway by altering phosphorylation and degradation mechanisms.

1 citation

proteomicsstatistical model

𝕏 PostBluesky