Wenzhe Ma

Degradation of amyloid beta species by multi-copper oxidases

This study identifies multi-copper oxidases (MCOs) as enzymes capable of degrading amyloid beta (Aβ) peptides, with ascorbate oxidase showing the strongest effect, and demonstrates their potential to mitigate Aβ-induced neuronal toxicity.

The self-regulated response of the Wnt pathway to an oncogenic mutation in β-catenin

The paper investigates how an oncogenic mutation in β-catenin affects the Wnt pathway by altering phosphorylation and degradation mechanisms.

Mechanical Coupling Coordinates the Co-elongation of Axial and Paraxial Tissues in Avian Embryos

The paper shows that mechanical interactions coordinate the elongation of axial and paraxial tissues in avian embryos through a feedback loop involving cell motility and compression.

Single molecule dynamics of Dishevelled at the plasma membrane and Wnt pathway activation

This study uses single-molecule imaging to analyze Dvl2 dynamics and oligomerization during Wnt pathway activation, showing increased oligomerization and dwell time upon Wnt3a stimulation.