Multiscale characterization of Caenorhabditis elegans mutants to probe functional mechanisms of human actin pathological variants
Théo Hecquet, Nadine Arbogast, Delphine Suhner, Anaïs Goetz, Grégory Amann, Selin Yürekli, Fiona Marangoni, Sophie Quintin, Johannes N. Greve, Nataliya Di Donato, Anne-Cécile Reymann
The paper uses C. elegans actin mutants to study human actinopathies, finding that mutation severity correlates with phenotypic defects in the worm model.
iScience · Sep 27, 2025Peer-reviewedCell Biology