Essential genes encoded by the mating-type locus of the human fungal pathogen Cryptococcus neoformans
Zhuyun Bian, Ziyan Zoe Xu, Anushka Peer, Yeseul Choi, Shelby J. Priest, Konstantina Akritidou, Ananya Dasgupta, Tim A. Dahlmann, Ulrich Kück, Minou Nowrousian, Matthew S. Sachs, Sheng Sun, Joseph Heitman
This study identifies essential genes in the mating-type locus of Cryptococcus neoformans, showing that four genes are essential for viability while MYO2 is critical for pathogenicity despite not being essential.
mBio · Feb 25, 2025Peer-reviewedGenetics