Ziyan Zoe Xu

This study identifies meiosis-specific genes critical for ploidy reduction in Cryptococcus neoformans titan cells, showing their role in generating stable diploid daughter cells.

This study shows that mutating the RIC8 gene in Cryptococcus neoformans enables unisexual reproduction involving meiotic recombination, suggesting it may be more common in nature than previously thought.

This study identifies essential genes in the mating-type locus of Cryptococcus neoformans, showing that four genes are essential for viability while MYO2 is critical for pathogenicity despite not being essential.

This study identifies R14, a phloroglucinol-terpene hybrid, as a novel EGFR inhibitor that protects podocytes from apoptosis through modulation of the PI3K/AKT/mTOR pathway.

The paper identifies RNAi loss-of-function mutations in Cryptococcus neoformans and shows they can lead to hypermutation when combined with transposon burdens.

The paper develops a computational method to analyze single-cell RNA-seq data to study cell-cell interactions in tumors, showing that CD40 agonist enhances immune checkpoint blockade by modulating myeloid-T cell interactions.