Perinatal liver inflammation is associated with persistent elevation of CXCL10 and its canonical receptor CXCR3 on common myeloid progenitors
Anas Alkhani, Suruthi Baskaran, Abhishek Murti, Blaine Rapp, Claire S. Levy, Bruce Wang, Amar Nijagal
This study shows that perinatal liver inflammation leads to long-term changes in myeloid progenitors through the CXCL10-CXCR3 axis, which may contribute to immune dysfunction in biliary atresia.
bioRxiv · Aug 15, 2024 · PreprintImmunology