Cancer BiologybioRxivPreprint
Characterization of the BRAF interactome identifies BRAFV600ETP53 interaction in melanoma
Kayla T. O’Toole, Adamaris Martinez, Brandon Murphy…·Martin McMahon
The paper identifies a novel interaction between BRAFV600E and TP53 in melanoma, suggesting that BRAFV600E inactivates TP53, explaining the rarity of TP53 alterations in this cancer type.
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