Four Salvage NAD+ Biosynthetic Pathway Enzymes Moonlight as Molecular Chaperones to Protect Against Proteotoxicity
Meredith Pinkerton, Andrea Ruetenik, Viktoriia Bazylianska, Eva Nývltová, Antoni Barrientos
The paper identifies four NAD+ biosynthetic enzymes that function as molecular chaperones to protect against proteotoxicity in neurodegenerative diseases.
Human Molecular Genetics · Mar 15, 2021Peer-reviewedNeuroscience