Alveolar macrophages initiate the spatially targeted neutrophil recruitment during nanoparticle inhalation
Qiongliang Liu, Lin Yang, Chenxi Li, Lianyong Han, Juliet Wilmot, Guo Yang, Riccardo Leinardi, Qiaoxia Zhou, Andreas Schröppel, David Kutschke, Judith Secklehner, Ali Önder Yildirim, François Huaux, Dagmar Zeuschner, Leo M. Carlin, , Markus Rehberg
The paper shows that alveolar macrophages recruit neutrophils to sites of nanoparticle deposition in the lung through motility, phagocytosis, and cytokine release.
Science Advances · Nov 7, 2025Peer-reviewedImmunology