Identification of 5-HT2A Receptor Signaling Pathways Responsible for Psychedelic Potential
Jason V. Wallach, Andrew B. Cao, Maggie M. Calkins, Andrew J. Heim, Janelle K. Lanham, Emma M. Bonniwell, Joseph J. Hennessey, Hailey A. Bock, Emilie I. Anderson, Alexander M. Sherwood, Hamilton Morris, Robbin de Klein, Adam K. Klein, Bruna Cuccurazzu, James M. Gamrat, , John D. McCorvy
The paper identifies 5-HT2A receptor signaling pathways that determine psychedelic potential using selective ligands and behavioral assays in mice.
bioRxiv · Jul 29, 2023 · PreprintNeuroscience