ONC201 in combination with ATR inhibitor ceralasertib exhibits potent synergy in ovarian cancer cells
Maryam Ghandali, Kadir Mert Selvi, Kelsey E. Huntington, Andrew George, Anna Ochsner, Benedito A. Carneiro, Don Steven Dizon, Leiqing Zhang, Wafik S. El‐Deiry
This study shows that combining ONC201 with ATR inhibitor ceralasertib synergistically kills ovarian cancer cells by inducing apoptosis and reducing anti-apoptotic proteins.
bioRxiv · Sep 24, 2026 · PreprintCancer Biology