Design principles of ROS dynamic networks relevant to precision therapies for age-related diseases
Alexey N. Kolodkin, Raju Prasad Sharma, Anna Maria Colangelo, Andrew Ignatenko, Francesca Martorana, Danyel G. J. Jennen, Jacob J. Briedé, Nathan Ryan Brady, Matteo Barberis, Thierry D.G.A. Mondeel, Michèle Papa, Vikas Kumar, Bernhard J. Peters, Alexander Skupin, Lilia Alberghina, , Hans Victor Westerhoff
The paper models the ROS regulatory network to show how its dysfunction contributes to age-related diseases like Parkinson's and suggests potential therapeutic interventions.
bioRxiv · May 29, 2019 · PreprintSystems Biology