Hans Victor Westerhoff

The paper compares kinetic models of E. coli ammonium transport and assimilation to determine the mechanism of energy coupling and growth robustness under varying conditions.

This study integrates gene expression and nutrient availability data to model metabolism in hepatocellular carcinoma, showing glucose affects proliferation and lactate production more than glutamine.

This study quantifies transcription bursting genome-wide in breast cancer cells using 4sUDRB-sequencing and finds burst sizes up to 160 transcripts, with correlations to promoter features and drug response.

The paper models the ROS regulatory network to show how its dysfunction contributes to age-related diseases like Parkinson's and suggests potential therapeutic interventions.

This paper integrates single-cell RNA-seq data into metabolic models to characterize tumour cell populations and identifies metabolic heterogeneity and interactions.