Author

Danyel G. J. Jennen

Maastricht UniversityORCID 0000-0002-8618-2487Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:benchmarking· 2 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:dimensionality reduction· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Alexander SkupiniD· 1 shared Alexey N. KolodkiniD· 1 shared Ammar AmmariD· 1 shared Andrew Ignatenko· 1 shared Anna Maria ColangeloiD· 1 shared Bernhard J. PetersiD· 1 shared Chris P.M. ReutelingspergeriD· 1 shared Chris T. EveloiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

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10 top collaborators · 21 mutual co-author links

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Alexander SkupinORCID

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3 papers

Recent·Most cited

User-friendly transcriptomic data analysis with ArrayAnalysis

J.C. Koetsier, Ozan Cinar, Egon Willighagen, Ammar Ammar, Vishnu Karthik, Danyel G. J. Jennen, Chris T. Evelo, Leopold Curfs, Chris P.M. Reutelingsperger, Nasim Bahram Sangani, Lars Eijssen

ArrayAnalysis provides an interactive web and desktop platform for analyzing microarray and RNA-seq data, offering tools for preprocessing, differential expression, and visualization to support both novice and expert users.

bioRxiv · Jul 18, 2026 · PreprintBioinformatics

Contextualization of causal regulatory networks from toxicogenomics data applied to drug-induced liver injury

Panuwat Trairatphisan, Terezinha Maria de Souza, Jos C. S. Kleinjans, Danyel G. J. Jennen, Julio Sáez-Rodríguez

The paper applies a causal network tool to toxicogenomics data to infer regulatory networks in drug-induced liver injury, identifying conserved pathways between rat and human models.

Toxicology Letters · Jul 3, 2021Peer-reviewedSystems Biology

Design principles of ROS dynamic networks relevant to precision therapies for age-related diseases

Alexey N. Kolodkin, Raju Prasad Sharma, Anna Maria Colangelo, Andrew Ignatenko, Francesca Martorana, Danyel G. J. Jennen, Jacob J. Briedé, Nathan Ryan Brady, Matteo Barberis, Thierry D.G.A. Mondeel, Michèle Papa, Vikas Kumar, Bernhard J. Peters, Alexander Skupin, Lilia Alberghina, , Hans Victor Westerhoff

The paper models the ROS regulatory network to show how its dysfunction contributes to age-related diseases like Parkinson's and suggests potential therapeutic interventions.

bioRxiv · May 29, 2019 · PreprintSystems Biology