Endothelial CXCL5 negatively regulates myelination and repair after white matter stroke
Guanxi Xiao, Rosie Kumar, Yutaro Komuro, Jasmine Burguet, Visesha Kakarla, Ida Azizkhanian, Sunil A. Sheth, Christopher Kazu Williams, Xinhai R. Zhang, Michal Macknicki, Andrew J. Brumm, Riki Kawaguchi, Phu Mai, Naoki Kaneko, Harry V. Vinters, , Jason D. Hinman
This study identifies CXCL5 as a negative regulator of myelination and repair after white matter stroke, mediated through endothelial signaling in a diet-induced obesity model.
bioRxiv · Jan 6, 2020 · PreprintNeuroscience