Leif A. Havton

Sarm1 is not necessary for activation of neuron-intrinsic growth programs yet required for the Schwann cell repair response and peripheral nerve regeneration.

Comparative specialization of intrinsic cardiac neurons in humans, mice, and pigs

This study compares intrinsic cardiac neurons across humans, mice, and pigs, revealing species-specific differences in structure, function, and neuropeptide expression.

Ultra-flexible and Stretchable Intrafascicular Peripheral Nerve Recording Device with Axon-dimension, Cuff-less Microneedle Electrode Array

This paper develops a flexible microneedle electrode array for peripheral nerve recording, demonstrating reduced tissue encapsulation and chronic reactivity in rats.

Screening for axon regeneration promoting compounds with human iPSC-derived motor neurons

This study identifies compounds that promote axon regeneration using human iPSC-derived motor neurons and validates blebbistatin as a top hit in vivo.

Innervation and Neuronal Control of the Mammalian Sinoatrial Node: A Comprehensive Atlas

The paper creates a comprehensive neuroanatomic atlas of the RAGP-SAN complex in porcine and human hearts, showing how intrinsic cardiac neurons control SAN automaticity and cardiac function.

Establishment of a Human Induced Pluripotent Stem Cell-Derived Neuromuscular Co-Culture Under Optogenetic Control

This paper establishes a hiPSC-derived neuromuscular co-culture system under optogenetic control to study NMJ formation and disease mechanisms.

Endothelial CXCL5 negatively regulates myelination and repair after white matter stroke

This study identifies CXCL5 as a negative regulator of myelination and repair after white matter stroke, mediated through endothelial signaling in a diet-induced obesity model.

Targeted complement inhibition at synapses prevents microglial synaptic engulfment and synapse loss in demyelinating disease

This study identifies synapse loss and microglial synaptic engulfment in MS models and demonstrates that targeted complement inhibition prevents synapse loss and visual dysfunction.

Obesity restricts oligodendrocyte maturation and impedes repair after white matter stroke

This study shows obesity impairs oligodendrocyte differentiation and remyelination after white matter stroke in mice.