Jason D. Hinman

Loss of Sarm1 Mitigates Axonal and Neuronal Degeneration and Promotes Neuronal Repair After Ischemic Stroke

This study shows that loss of Sarm1 reduces axonal degeneration and promotes neuronal repair after ischemic stroke by activating a pro-growth molecular program.

Sexually dimorphic differences in angiogenesis markers predict brain aging trajectories

The paper examines associations between circulating angiogenesis markers and brain aging trajectories in humans, finding sex-specific effects and implications for vascular cognitive impairment.

Endothelial CXCL5 negatively regulates myelination and repair after white matter stroke

This study identifies CXCL5 as a negative regulator of myelination and repair after white matter stroke, mediated through endothelial signaling in a diet-induced obesity model.

Endothelial-derived exosomes demonstrate a link between endothelial innate inflammation and brain dysfunction and injury in aging

The paper examines endothelial-derived exosomes in older adults to link endothelial inflammation with white matter injury, cognition, and brain degeneration.

Obesity restricts oligodendrocyte maturation and impedes repair after white matter stroke

This study shows obesity impairs oligodendrocyte differentiation and remyelination after white matter stroke in mice.