NMDAR-activated PP1 dephosphorylates GluN2B to modulate NMDAR synaptic content.
Andrew M. Chiu, Jiejie Wang, Michael Patrick Fiske, Pavla Hubálková, Levi W. Barse, John A. Gray, Antonio Sanz-Clemente
The paper identifies phosphorylation of GluN2B at S1480 as a mechanism controlling NMDAR synaptic content through PP1-mediated dephosphorylation.
Cell Reports · Jul 1, 2019Peer-reviewedNeuroscience