Interaction between time-of-day and oxytocin efficacy in mice and humans with and without gestational diabetes
Thu Van-Quynh Duong, Alexandra M. Yaw, Guoli Zhou, Niharika Sinha, Aneesh Sai Cherukuri, Duong Nguyen, Kylie Cataldo, Nicollette Ly, Aritro Sen, Lorenzo F. Sempere, Cara Detrie, Robert Seiler, Isoken Nicholas Olomu, Rene Cortese, Robert Long, Hanne Mette Hoffmann
The paper investigates how time-of-day and Bmal1 affect oxytocin efficacy in mice and humans with gestational diabetes, finding time-dependent effects and suggesting morning Pitocin administration for diabetic pregnancies.
Molecular Metabolism · Oct 17, 2025Peer-reviewedPhysiology