Author

Anika Klaus

Humboldt-Universität zu Berlin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Alice VitaliiD· 1 shared Angelika EggertiD· 1 shared Annette KünkeleiD· 1 shared Anton George HensseniD· 1 shared Carlotta Caramel· 1 shared Falk HertwigiD· 1 shared Frank WestermanniD· 1 shared Gabriele BücheliD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Alice VitaliORCID

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1 paper

Recent·Most cited

ImmunologyPharmacological ResearchPeer-reviewedJan 18, 2025

Targeting MYCN upregulates L1CAM tumor antigen in MYCN-dysregulated neuroblastoma to increase CAR T cell efficacy

Laura Grunewald, Lena Andersch, Konstantin Helmsauer…·Annette Künkele

This paper shows that high MYCN levels in neuroblastoma reduce L1CAM expression, limiting CAR T cell efficacy, and that inhibiting MYCN with MLN8237 restores L1CAM and enhances CAR T cell activity.

8 citations

humanbulk RNA-seq

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