BiophysicsbioRxivPreprint
Mapping Structural Drivers of Insulin and its Analogs at the IGF-1 Receptor Using Molecular Dynamics and Free Energy Calculations
Mohan Maruthi Sena, Ramakrishnan C, M. Michael Gromiha…·Anirudh Ranganathan
This study uses molecular dynamics and free energy calculations to predict insulin analog potency at IGF-1R and identify structural drivers of activity.
DOI 10.1101/2023.12.02.569705