Systems BiologybioRxivPreprint
A Computational Model of Tumor Interactions with Bone-Resident Cells Predicts Tumor-Type-Specific Responses to Perturbations
Alexandra Gutierrez Vega, Natalie E. Bennett, Erik P. Beadle…·L. Lynn Harris
This paper develops a computational model of tumor-bone interactions to predict how different tumor types respond to perturbations, showing that bone-adapted tumors are less dependent on bone-derived growth factors and less responsive to OC-targeted therapy.
DOI 10.64898/2026.02.16.706164