IL-7 armed binary CAR T cell strategy to augment potency against solid tumors
Alejandro G. Torres Chavez, Mary Kathryn McKenna, Anmol Gupta, Neha Daga, Juan F. Vera, Ann Marie Leen, Pradip Bajgain
This study develops a binary CAR T cell strategy targeting PSCA and MUC1 with IL-7 expression to improve antitumor potency and persistence in pancreatic tumors.
Frontiers in Immunology · Jul 30, 2025Peer-reviewedImmunology