An isogenic human iPSC model unravels neurodevelopmental abnormalities in SMA
Tobias Graß, Ines Rosignol, Joshua D. Thomas, Felix Buchner, Zeynep Dokuzluoglu, Anna Dalinskaya, Jutta Becker, Brunhilde Wirth, Natalia Rodríguez‐Muela
This study uses an isogenic human iPSC model to show altered neural progenitor and motor neuron markers in SMA, suggesting developmental defects may contribute to neuronal death.
bioRxiv · Jan 2, 2023 · PreprintNeuroscience