Author

Anna L M Smith

Wellcome Centre for Mitochondrial Research

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Genetics· 1

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Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Alasdair P. BlainiD· 1 shared Conor LawlessiD· 1 shared Douglass M. TurnbulliD· 1 shared James Bruce StewartiD· 1 shared Julia C. WhitehalliD· 1 shared Laura C. GreavesiD· 1 shared Louisa Scholten· 1 shared Marie‐Lune SimardiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Alasdair P. BlainORCID

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1 paper

Recent·Most cited

Cell division can accelerate the loss of a heteroplasmic mitochondrial DNA mutation in a mouse model of mitochondrial disease

Tianhong Su, Tiago M. Bernardino Gomes, Anna L M Smith, Julia C. Whitehall, Alasdair P. Blain, Marie‐Lune Simard, Louisa Scholten, James Bruce Stewart, Douglass M. Turnbull, Conor Lawless, Laura C. Greaves

The paper shows that cell division reduces mtDNA mutation load in mitotic tissues of a mouse model, while post-mitotic tissues maintain stable mutation levels.

bioRxiv · Apr 6, 2023 · PreprintGenetics