Genetically interacting mutations and mechanical stress affect the stochasticity of developmental eye defects in yap1 mutants
Niccolò Fioritti, Mahum Shaikh, Giulia Cazzagon, Gareth T. Powell, Kate Turner, lisa tucker, Anna Mallucci, Evdokia Hadjieconomou, Stephen P. Carter, Daniel Wehner, Gilbert Weidinger, Richard J. Poole, Florencia Cavodeassi, Leonardo E. Valdivia, Rodrigo Young, , Gaia Gestri
The paper investigates stochastic developmental eye defects in zebrafish yap1 mutants, showing genetic and mechanical factors influence penetrance of retinal coloboma.
bioRxiv · Jul 17, 2026 · PreprintDevelopmental Biology