Gilbert Weidinger

The paper shows that blastema cells in zebrafish fin regeneration have intrinsic migratory capacity but osteoblasts do not migrate off the bone unless multiple injuries are present.

This study identifies mTOR signaling as a central regulator of zebrafish heart regeneration, showing its dual role in promoting cardiomyocyte proliferation and regulating autophagy.

The paper investigates stochastic developmental eye defects in zebrafish yap1 mutants, showing genetic and mechanical factors influence penetrance of retinal coloboma.

The paper identifies Laudanosine as an inhibitor of TPC2-dependent viral entry, effective against Ebola and related viruses without cytotoxicity.

This study identifies the Man-PTS as a receptor for Angicin in streptococci and defines structural features associated with its antimicrobial activity.

CRISPR screens with replication-competent SIVcpz identify human antiviral factors limiting efficient viral replication after zoonotic transmission.

The paper shows that Wnt/β-catenin signaling via wnt10a inhibits NF-κB to induce osteoblast dedifferentiation in zebrafish, which is also observed in cardiomyocytes during heart regeneration.

This study shows that circadian rhythms in glycolysis and cell cycle progression are essential for cardiomyocyte proliferation and heart regeneration in zebrafish.

This paper optimizes a HIV-1 entry inhibitor peptide using ReaxFF molecular dynamics simulations, reducing its size while maintaining or improving antiviral activity.

This study shows BMP signaling alleviates replication stress in cardiomyocytes, enabling heart regeneration in zebrafish and potentially applicable to humans.

This study identifies BMP7 as a key growth factor promoting cardiomyocyte proliferation in both mouse and zebrafish models, with potential therapeutic applications for heart regeneration.

This study shows that osteoblast dedifferentiation and migration are distinct, differentially regulated processes required for zebrafish fin regeneration.

The paper quantifies cardiomyocyte regeneration in zebrafish after injury, finding complete numerical replacement but incomplete differentiation and scar resorption.

The paper investigates how EPI-X4 binds to CXCR4 using simulations and experiments, leading to the design of more potent and safer CXCR4 antagonists.