Segmentation Matters: Recognizing the Cell Segmentation Challenge in Spatial Transcriptomics
Huasheng Yu, Anna Yao Carroll, Kevin Shen, Nathan Wu, Hanying Yan, Jingwei Xiong, Miguel Francisco Mercado, Eric A. Kaiser, Mayank Gautam, Mingyao Li, Wenqin Luo
The paper evaluates segmentation methods in spatial transcriptomics, showing that manual review is necessary due to model-specific errors.
bioRxiv · Aug 25, 2025 · PreprintNeuroscience