Design and Characterisation of Photoactivatable and Lysine Reactive o-Nitrobenzyl Alcohol-Based Crosslinkers
Adam Cahill, Martin Walko, Benjamin A. Fenton, Sri Ranjani Ganji, Anne Herbert, Sheena E. Radford, Nikil Kapur, Keith Livingstone, Megan H. Wright, Antonio N. Calabrese
This study develops and characterizes oNBA-based crosslinkers for structural proteomics, showing high labelling efficiency and crosslinking yields with optimized photolysis conditions.
Chemical Science · Jan 1, 2025Peer-reviewedBiophysics