Microbiota-dependent IFN-L controls uterine and placental immunity.
Elisha Segrist, Anne Roman, Eduard Ansaldo, Juliana Perez Chaparro, Colton M McNinch, Irini Sereti, Yasmine Belkaid
This study identifies IFN-L as a microbiota-dependent regulator of uterine immunity, controlling both immunoregulation and antibacterial responses during pregnancy.
bioRxiv · Jan 29, 2026 · PreprintImmunology