Hotwiring integrin endocytosis acutely modulates cell interactions
Sahil Kamboj, Alphonse Boché, Anneline Moret, Zixu Wang, Carole Aimé, Rémy Agniel, Johanne Leroy‐Dudal, Franck Carreiras, Olivier Gallet, Stephen J Royle, Ambroise Lambert
This study uses hot-wired endocytosis to acutely downregulate 5{beta}1 integrins, showing reduced cell area, fibronectin uptake, and slower tumor spheroid compaction.
bioRxiv · Jun 24, 2024 · PreprintBioengineering