Alphonse Boché

This study shows that ovarian cancer cell migration is strongly influenced by extracellular matrix composition, with fibronectin and TGF-β synergistically enhancing migration and EMT markers.

The paper uses single cell phenomics to show that combining cytokines additively enhances EMT in cancer cell lines, regardless of their baseline EMT state.

This paper develops virus-like particles (VLPs) displaying ECM peptides to control cell functions and demonstrates their effectiveness in promoting adhesion, migration, proliferation, and differentiation.

This study uses hot-wired endocytosis to acutely downregulate 5{beta}1 integrins, showing reduced cell area, fibronectin uptake, and slower tumor spheroid compaction.