Mycobacteriophage TM4 requires XylR for successful infection in Mycobacterium smegmatis mc2155
Annesha Adhikari, Tejan Lodhiya, Subhashree Nayak, Rohit Satardekar, Raju Mukherjee
This study identifies a phage resistance mechanism in Mycobacterium smegmatis involving XylR-mediated cell-envelope remodeling that impedes phage DNA injection.
bioRxiv · May 17, 2026 · PreprintMicrobiology