A platform of robust patient-derived leukemia models covering subgroups for which no cell lines exist
Binje Vick, Vindi Jurinović, Kristina Kuhbandner, Lena Lagally, Lisa Latzko, Chiara Arnreich, Gerulf Hänel, Amelie Muth, Maja Rothenberg‐Thurley, Annika Maria Dufour, Stephanie E. Schneider, Lesca Miriam Holdt, Liliana Mura, Fabian Klein, Annette Frank, , Irmela Jeremias
The paper develops patient-derived AML PDX models that replicate primary AML biology and include subgroups lacking existing models, showing reduced leukemia growth after long-term chemotherapy.
bioRxiv · Sep 26, 2025 · PreprintCancer Biology