Integrated scFv identification and CAR T cell generation for AML targeting in vivo
Yi Liu, Annika Lauk, David N. Sedloev, Josephine Brysting, Ela Cetin, C.T. Liu, Maximilian Mönnig, Thomas Luft, Haiyang Yun, Michael W. Schmitt, Tim Sauer, Fengbiao Zhou, Christian Rohde, Carsten Müller‐Tidow
This study integrates scFv development with CAR T cell generation to target CLL1-positive AML, showing effective tumor killing in vivo.
International Journal of Cancer · Oct 2, 2025Peer-reviewedImmunology