Dysregulated dsRNA sensor signaling and viral infection during onset of pediatric autoimmune interferonopathy
THOMAS RJ MOREAU, Yann Aquino, Y.Y.J. Zhu, Vincent Bondet, Chloé Albert Vega, Françoise Donnadieu, Florian Dubois, Baptiste Periou, F. Rahal, MINA TIZERARINE, Saskia R Veldkamp, Étienne Villain, ANTHONY BERTRAND, Christine Bodemer, Camille Brunaud, , Darragh Duffy
The paper identifies dysregulated dsRNA sensing and RNA viral exposure as potential triggers of type I interferon dysregulation in juvenile dermatomyositis onset.
bioRxiv · May 29, 2026 · PreprintImmunology