Nested Russian Doll-like Genetic Mobility Drives Rapid Dissemination of the Carbapenem Resistance Gene blaKPC
Anna E Sheppard, Nicole Stoesser, Daniel J Wilson, Robert Sebra, Andrew Kasarskis, Luke W Anson, Adam Giess, Louise J Pankhurst, Alison Vaughan, Christopher J Grim, Heather L Cox, Anthony J Yeh, the Modernising Medical Microbiology (MMM) Informa, Costi D Sifri, A. Sarah Walker, , Amy J Mathers
This paper tracks the rapid spread of the blaKPC resistance gene in a hospital over five years, revealing nested genetic mobility mechanisms that enable dissemination across species and plasmids.
Antimicrobial Agents and Chemotherapy · Jun 1, 2016Peer-reviewedMicrobiology