Andrew Kasarskis

The paper uses measured and predicted gene expression to identify ulcerative colitis patients at elevated risk of colectomy, showing both methods independently replicate in multiple datasets.

This study identifies shared molecular signatures between chronic fatigue syndrome and other fatiguing illnesses using RNA-sequencing data from blood samples.

This study characterizes the epigenome of C. difficile and identifies a conserved DNA methyltransferase that impacts sporulation and other biological processes.

This paper tracks the rapid spread of the blaKPC resistance gene in a hospital over five years, revealing nested genetic mobility mechanisms that enable dissemination across species and plasmids.

This study traces the evolutionary history of the ST131 E. coli lineage, showing its clonal expansion linked to antibiotic use and plasmid acquisition, with implications for antimicrobial resistance control.